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Antiallodynic and anti-inflammatory effects of intrathecal R-PIA in a rat model of vincristine-induced peripheral neuropathy

BACKGROUND: Studies investigating the correlation between spinal adenosine A(1) receptors and vincristine-induced peripheral neuropathy (VIPN) are limited. This study explored the role of intrathecal N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) in the rat model of VIPN. METHODS: Vincristine...

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Publicat a:Korean J Anesthesiol
Autors principals: Kim, Kyungmi, Jeong, Wonyeong, Jun, In Gu, Park, Jong Yeon
Format: Artigo
Idioma:Inglês
Publicat: Korean Society of Anesthesiologists 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533172/
https://ncbi.nlm.nih.gov/pubmed/32046474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kja.19481
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