Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts

The widespread use of therapeutic glucocorticoids has increased the frequency of glucocorticoid-induced osteoporosis (GIOP). One of the potential pathological processes of GIOP is an increased level of oxidative stress and mitochondrial dysfunction, which eventually leads to osteoblast apoptosis. Pr...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Chen, Liang, Hu, Sun-Li, Xie, Jun, Yan, De-Yi, Weng, She-Ji, Tang, Jia-Hao, Wang, Bing-Zhang, Xie, Zhong-Jie, Wu, Zong-Yi, Yang, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533007/
https://ncbi.nlm.nih.gov/pubmed/33062149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9102012
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