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Requirement for Serine-384 in Caspase-2 processing and activity

Caspase-2 is a unique and conservative cysteine protease which plays an important role in several cellular processes including apoptotic cell death. Although the molecular mechanisms of its activation remain largely unclear, a major role belongs to the architecture of the caspase-2 active center. We...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Zamaraev, Alexey V., Volik, Pavel I., Nilov, Dmitry K., Turkina, Maria V., Egorshina, Aleksandra Yu., Gorbunova, Anna S., Iarovenko, Svetlana Iu., Zhivotovsky, Boris, Kopeina, Gelina S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532978/
https://ncbi.nlm.nih.gov/pubmed/33011746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03023-6
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