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A Tetramer Derived from Islet Amyloid Polypeptide
Aggregation of the islet amyloid polypeptide (IAPP) to form fibrils and oligomers is important in the progression of type 2 diabetes. This paper describes X-ray crystallographic and solution-state NMR studies of peptides derived from residues 11–17 of IAPP that assemble to form tetramers. Incorporat...
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| Veröffentlicht in: | J Org Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7532939/ https://ncbi.nlm.nih.gov/pubmed/28661686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01116 |
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