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Whole-genome and enzymatic analyses of an androstenedione-producing Mycobacterium strain with residual phytosterol-degrading pathways

Mycobacterium neoaurum strains can transform phytosterols to 4-androstene-3,17-dione (4-AD), a key intermediate for the synthesis of advanced steroidal medicines. In this work, we presented the complete genome sequence of the M. neoaurum strain HGMS2, which transforms β-sitosterol to 4-AD. Through g...

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Bibliografske podrobnosti
izdano v:Microb Cell Fact
Main Authors: Wang, Hongwei, Song, Shikui, Peng, Fei, Yang, Fei, Chen, Tian, Li, Xin, Cheng, Xiyao, He, Yijun, Huang, Yongqi, Su, Zhengding
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532642/
https://ncbi.nlm.nih.gov/pubmed/33008397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01442-w
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