Highly multiplexed quantifications of 299 somatic mutations in colorectal cancer patients by automated MALDI-TOF mass spectrometry

BACKGROUND: Detection of somatic mutations in tumor tissues helps to understand tumor biology and guide treatment selection. Methods such as quantitative PCR can analyze a few mutations with high efficiency, while next generation sequencing (NGS) based methods can analyze hundreds to thousands of mu...

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Publicat a:BMC Med Genomics
Autors principals: Xu, Chang, Peng, Danli, Li, Jialu, Chen, Meihua, Hu, Yujie, Hou, Mingliang, Shang, Qingjuan, Liang, Qi, Li, Jie, Li, Wenfeng, Wu, Xiaoli, Liu, Changbao, Hu, Wanle, Cai, Mao, Zhang, Huxiang, Chen, Guorong, Yu, Lingling, Zheng, Xiaoqun, Jiang, Feizhao, Luan, Ju, Jin, Shengnan, Ding, Chunming
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532609/
https://ncbi.nlm.nih.gov/pubmed/33008377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00804-y
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