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Epigenetic silencing of CDKN1A and CDKN2B by SNHG1 promotes the cell cycle, migration and epithelial-mesenchymal transition progression of hepatocellular carcinoma

Enhanced SNHG1 (small nucleolar RNA host gene 1) expression has been found to play a critical role in the initiation and progression of hepatocellular carcinoma (HCC) with its detailed mechanism largely unknown. In this study, we show that SNHG1 promotes the HCC progression through epigenetically si...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Bei, Li, Ang, You, Zhen, Xu, Jingchang, Zhu, Sha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532449/
https://ncbi.nlm.nih.gov/pubmed/33009370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03031-6
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