Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma

INTRODUCTION: Multiple myeloma (MM) is an extremely malignant and incurable hematological cancer. Increased expression of the c-Myc oncoprotein is closely associated with shorter overall survival of MM patients, implying that c-Myc is a potential therapeutic target. MAIN METHODS: We identified a pot...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Yao, Ruosi, Xie, Yu, Sun, Xiaoyang, Zhang, Menghui, Zhou, Jian, Liu, Linlin, Gao, Jian, Xu, Kailin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532311/
https://ncbi.nlm.nih.gov/pubmed/33061303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S264077
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