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Trigonelline recovers memory function in Alzheimer’s disease model mice: evidence of brain penetration and target molecule
Trigonelline (TGN; 1-methylpyridin-1-ium-3-carboxylate) is a widely distributed alkaloid derived from plants. Since we previously found a neurite outgrowth effect of TGN, we hypothesised that TGN might help to improve memory deficits. Here, the efficacy of TGN in restoring amyloid β (Aβ)-induced axo...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7532147/ https://ncbi.nlm.nih.gov/pubmed/33009465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73514-1 |
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