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Influence of Polyvinyl Alcohol (PVA) on PVA-Poly-N-hydroxyethyl-aspartamide (PVA-PHEA) Microcrystalline Solid Dispersion Films

This study was conducted to formulate buccal films consisting of polyvinyl alcohol (PVA) and poly-N-hydroxyethyl-aspartamide (PHEA), to improve the dissolution of the drug through the oral mucosa. Ibuprofen sodium salt was used as a model drug, and the buccal film was expected to enhance its dissolu...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Al-Sahaf, Zahra, Raimi-Abraham, Bahijja, Licciardi, Mariano, de Mohac, Laura Modica
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532132/
https://ncbi.nlm.nih.gov/pubmed/33006710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-020-01811-z
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