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Enabling speed to clinic for monoclonal antibody programs using a pool of clones for IND-enabling toxicity studies

The importance of speed to clinic for medicines that may address unmet medical needs puts pressure on product development timelines. Historically, both toxicology and first-in-human clinical materials are generated using the same clonal-derived cells to ensure safety and minimize any development ris...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Bolisetty, Parimala, Tremml, Gabi, Xu, Sen, Khetan, Anurag
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531531/
https://ncbi.nlm.nih.gov/pubmed/32449878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1763727
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