Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions

Monoclonal antibodies are a class of biotherapeutics used for an increasing variety of disorders, including cancer, autoimmune, neurodegenerative, and viral diseases. Besides their antigen specificity, therapeutic use also mandates control of their solution interactions and colloidal properties in o...

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Dades bibliogràfiques
Publicat a:MAbs
Autors principals: Chaturvedi, Sumit K., Parupudi, Arun, Juul-Madsen, Kristian, Nguyen, Ai, Vorup-Jensen, Thomas, Dragulin-Otto, Sonia, Zhao, Huaying, Esfandiary, Reza, Schuck, Peter
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531506/
https://ncbi.nlm.nih.gov/pubmed/32887536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1810488
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