Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations

BACKGROUND: Osimertinib, a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI), can be used as second-line treatment for lung cancer patients harboring the T790M substitution. Although osimertinib is more effective than the first-generation EGFR-TKIs used for fir...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Takeda, Yuichiro, Naka, Go, Yamaguchi, Yoh, Hashimoto, Masao, Suzuki, Manabu, Izumi, Shinyu, Sugiyama, Haruhito
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531095/
https://ncbi.nlm.nih.gov/pubmed/33008313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07424-w
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