Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans

Maternal mRNA clearance is an essential process that occurs during maternal-to-zygotic transition (MZT). However, the dynamics, functional importance, and pathological relevance of maternal mRNA decay in human preimplantation embryos have not yet been analyzed. Here we report the zygotic genome acti...

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Pubblicato in:Nat Commun
Autori principali: Sha, Qian-Qian, Zheng, Wei, Wu, Yun-Wen, Li, Sen, Guo, Lei, Zhang, Shuoping, Lin, Ge, Ou, Xiang-Hong, Fan, Heng-Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530992/
https://ncbi.nlm.nih.gov/pubmed/33004802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18680-6
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