Hidden Microatelectases Increase Vulnerability to Ventilation-Induced Lung Injury

Mechanical ventilation of lungs suffering from microatelectases may trigger the development of acute lung injury (ALI). Direct lung injury by bleomycin results in surfactant dysfunction and microatelectases at day 1 while tissue elastance and oxygenation remain normal. Computational simulations of a...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Albert, Karolin, Krischer, Jeanne-Marie, Pfaffenroth, Alexander, Wilde, Sabrina, Lopez-Rodriguez, Elena, Braun, Armin, Smith, Bradford J., Knudsen, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530907/
https://ncbi.nlm.nih.gov/pubmed/33071807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.530485
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