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Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers

Telomerase reverse transcriptase (TERT) is pathologically expressed in the vast majority of human cancers, but the epigenetic regulation of its expression is only beginning to be understood. In particular, the active TERT gene in cancer cells has been characterized as having a hypermethylated CpG is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Rowland, Teisha J., Bonham, Andrew J., Cech, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530785/
https://ncbi.nlm.nih.gov/pubmed/33245585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12786
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