ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis

Liver tests (LT), especially to measure AST, ALT and GGT levels, are widely used to evaluate the risk of alcohol-related liver disease (ALD). In this study, we investigated the potential genetic factors that modulate the association between LTs and alcohol consumption. We conducted a genome-wide int...

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Vydáno v:Sci Rep
Hlavní autoři: Sutoh, Yoichi, Hachiya, Tsuyoshi, Suzuki, Yuji, Komaki, Shohei, Ohmomo, Hideki, Kakisaka, Keisuke, Wang, Ting, Takikawa, Yasuhiro, Shimizu, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530747/
https://ncbi.nlm.nih.gov/pubmed/33004991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73263-1
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