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Sclerostin antibody stimulates periodontal regeneration in large alveolar bone defects

Destruction of the alveolar bone in the jaws can occur due to periodontitis, trauma or following tumor resection. Common reconstructive therapy can include the use of bone grafts with limited predictability and efficacy. Romosozumab, approved by the FDA in 2019, is a humanized sclerostin-neutralizin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yao, Yao, Kauffmann, Frederic, Maekawa, Shogo, Sarment, Lea V., Sugai, James V., Schmiedeler, Caroline A., Doherty, Edward J., Holdsworth, Gill, Kostenuik, Paul J., Giannobile, William V.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530715/
https://ncbi.nlm.nih.gov/pubmed/33004873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73026-y
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