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Clonal hematopoiesis: mechanisms driving dominance of stem cell clones
The discovery of clonal hematopoiesis (CH) in older individuals has changed the way hematologists and stem cell biologists view aging. Somatic mutations accumulate in stem cells over time. While most mutations have no impact, some result in subtle functional differences that ultimately manifest in d...
Tallennettuna:
| Julkaisussa: | Blood |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530644/ https://ncbi.nlm.nih.gov/pubmed/32746453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006510 |
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