Vortioxetine induces apoptosis and autophagy of gastric cancer AGS cells via the PI3K/AKT pathway

Vortioxetine is a potent antagonist of the 5‐hydroxytryptamine receptor and serotonin transporter and has been reported to function as an antidepressant in the treatment of major depressive disorder. However, its antitumor effects remain unclear. Here, we examined whether vortioxetine affects the ch...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Lv, Gao‐Bo, Wang, Ting‐Ting, Zhu, Hai‐Lin, Wang, Hong‐Ke, Sun, Wen, Zhao, Li‐Feng
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530385/
https://ncbi.nlm.nih.gov/pubmed/32750222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12944
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