Exposure to Morphine and Caffeine Induces Apoptosis and Mitochondrial Dysfunction in a Neonatal Rat Brain

Background: Preterm infants experience rapid brain growth during early post-natal life making them vulnerable to drugs acting on central nervous system. Morphine is administered to premature neonates for pain control and caffeine for apnea of prematurity. Simultaneous use of morphine and caffeine is...

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Bibliographic Details
Published in:Front Pediatr
Main Authors: Kasala, Sweatha, Briyal, Seema, Prazad, Preetha, Ranjan, Amaresh K., Stefanov, Gospodin, Donovan, Ramona, Gulati, Anil
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Pediatrics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530195/
https://ncbi.nlm.nih.gov/pubmed/33042927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.00593
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