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Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis

It is currently believed that innate immunity is unable to prevent the spread of SARS-CoV-2 from the upper airways to the alveoli of high-risk groups of patients. SARS-CoV-2 replication in ACE-2-expressing pneumocytes can drive the diffuse alveolar injury through the cytokine storm and immunothrombo...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Motta Junior, Jarbas da Silva, Miggiolaro, Anna Flavia Ribeiro dos Santos, Nagashima, Seigo, de Paula, Caroline Busatta Vaz, Baena, Cristina Pellegrino, Scharfstein, Julio, de Noronha, Lucia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530169/
https://ncbi.nlm.nih.gov/pubmed/33042157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.574862
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