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Perinatal nicotine reduces chemosensitivity of medullary 5-HT neurons after maturation in culture.
Perinatal exposure to nicotine produces ventilatory and chemoreflex deficits in neonatal mammals. Medullary 5-HT neurons are putative central chemoreceptors that innervate respiratory nuclei and promote ventilation, receive cholinergic input and express nicotinic acetylcholine receptors (nAChRs). Pe...
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| Gepubliceerd in: | Neuroscience |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530107/ https://ncbi.nlm.nih.gov/pubmed/32818601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.08.012 |
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