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Campafungins: Inhibitors of Candida albicans and Cryptococcus neoformans Hyphal Growth

Campafungin A is a polyketide that was recognized in the Candida albicans fitness test due to its antiproliferative and antihyphal activity. Its mode of action was hypothesized to involve inhibition of a cAMP-dependent PKA pathway. The originally proposed structure appeared to require a polyketide a...

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Bibliographische Detailangaben
Veröffentlicht in:J Nat Prod
Hauptverfasser: Perlatti, Bruno, Harris, Guy, Nichols, Connie B., Ekanayake, Dulamini I., Alspaugh, J. Andrew, Gloer, James B., Bills, Gerald F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530089/
https://ncbi.nlm.nih.gov/pubmed/32881504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.0c00641
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