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Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro-myelinating genes

Ascorbic acid (vitamin C) is critical for Schwann cells to myelinate peripheral nerve axons during development and remyelination after injury. However, its exact mechanism remains elusive. Vitamin C is a dietary nutrient that was recently discovered to promote active DNA demethylation. Schwann cell...

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Bibliografische gegevens
Gepubliceerd in:J Neurochem
Hoofdauteurs: Huff, Tyler C., Sant, David W., Camarena, Vladimir, Van Booven, Derek, Andrade, Nadja S., Mustafi, Sushmita, Monje, Paula V., Wang, Gaofeng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530063/
https://ncbi.nlm.nih.gov/pubmed/32219848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15015
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