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A weak link with actin organizes tight junctions to control epithelial permeability

In vertebrates, epithelial permeability is regulated by the tight junction (TJ) formed by specialized adhesive membrane proteins, adaptor proteins, and the actin cytoskeleton. Despite the TJ’s critical physiological role, a molecular-level understanding of how TJ assembly sets the permeability of ep...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Belardi, Brian, Hamkins-Indik, Tiama, Harris, Andrew R., Kim, Jeongmin, Xu, Ke, Fletcher, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530003/
https://ncbi.nlm.nih.gov/pubmed/32841596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.07.022
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