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Disrupted place cell remapping and impaired grid cells in knock-in model of Alzheimer’s disease
Patients with Alzheimer’s disease (AD) suffer from spatial memory impairment and wandering behavior, but brain circuit mechanisms causing such symptoms remain largely unclear. In healthy brains, spatially-tuned hippocampal place cells and entorhinal grid cells exhibit distinct spike patterns in diff...
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| Publicado no: | Neuron |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529950/ https://ncbi.nlm.nih.gov/pubmed/32697942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.06.023 |
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