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Microbiota-derived metabolite promotes HDAC3 activity in the gut

The coevolution of mammalian hosts and their beneficial commensal microbes has led to development of a symbiotic host-microbiota relationship(1). Epigenetic machinery permits mammalian cells to integrate environmental signals(2), however, how these pathways are finely tuned by diverse cues from comm...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Wu, Shu-en, Hashimoto-Hill, Seika, Woo, Vivienne, Eshleman, Emily M., Whitt, Jordan, Engleman, Laura, Karns, Rebekah, Denson, Lee A., Haslam, David B., Alenghat, Theresa
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529926/
https://ncbi.nlm.nih.gov/pubmed/32731255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2604-2
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