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NKG2D-Fc fusion protein promotes antitumor immunity through the depletion of immunosuppressive cells

A major factor impeding the success of numerous therapeutic approaches in cancer is the immunosuppressive nature of the tumor microenvironment (TME). Hence, methods capable of reverting tumor immunosuppression through depletion or reprogramming of myeloid-derived suppressive cells (MDSCs) and regula...

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Publicat a:Cancer Immunol Immunother
Autors principals: Feng, Po-Hao, Lam, Brandon, Tseng, Ssu-Hsueh, Kung, Yu-Jui, Farmer, Emily, Cheng, Max A., Hung, Chien-Fu
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529872/
https://ncbi.nlm.nih.gov/pubmed/32468232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02615-7
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