Caspase-based PET for Evaluating Pro-Apoptotic Treatments in a Tuberculosis Mouse Model

PURPOSE: Despite recent advances in antimicrobial treatments, tuberculosis (TB) remains a major global health threat. Mycobacterium tuberculosis proliferates in macrophages preventing apoptosis by inducing anti-apoptotic proteins leading to necrosis of the infected cells. Necrosis then leads to incr...

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Bibliographic Details
Published in:Mol Imaging Biol
Main Authors: Ordonez, Alvaro A., Abhishek, Sudhanshu, Singh, Alok K., Klunk, Mariah H., Azad, Babak Benham, Aboagye, Eric O., Carroll, Laurence S., Jain, Sanjay K.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529691/
https://ncbi.nlm.nih.gov/pubmed/32232626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01494-9
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