Undetectable RAS-Mutant Clones in Plasma: Possible Implication for Anti-EGFR Therapy and Prognosis in Patients With RAS-Mutant Metastatic Colorectal Cancer

PURPOSE: Combining cetuximab with chemotherapy provides clinical benefit to 60% of the patients with RAS wild-type (RAS-wt) metastatic colorectal cancer (mCRC). This pilot study investigated the efficacy of cetuximab-based chemotherapy in a sample of patients (40%) with RAS mutation (RAS-mt) in thei...

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Bibliografiske detaljer
Udgivet i:JCO Precis Oncol
Main Authors: Bouchahda, Mohamed, Saffroy, Raphael, Karaboué, Abdoulaye, Hamelin, Jocelyne, Innominato, Pasquale, Saliba, Faouzi, Lévi, Francis, Bosselut, Nelly, Lemoine, Antoinette
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2020
Fag:
Original Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529530/
https://ncbi.nlm.nih.gov/pubmed/33015528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00400
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