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Smart Thermosensitive Copolymer Incorporating Chitosan-Zinc-Insulin Electrostatic Complexes for Controlled Delivery of Insulin: Effect of Chitosan Chain Length
This work was designed to optimize thermosensitive copolymeric depot-based system for delivering insulin at a controlled rate for a prolonged period following a single subcutaneous injection. Intrinsic ability of insulin to form hexamers in the presence of zinc and electrostatic complexes with chito...
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| Publicado en: | Int J Polym Mater |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529327/ https://ncbi.nlm.nih.gov/pubmed/33012880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00914037.2019.1655750 |
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