Zika virus-based immunotherapy enhances long-term survival of rodents with brain tumors through upregulation of memory T-cells

Zika virus (ZIKV) exhibits a tropism for brain tumor cells and has been used as an oncolytic virus to target brain tumors in mice with modest effects on extending median survival. Recent studies have highlighted the potential for combining virotherapy and immunotherapy to target cancer. We postulate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Crane, Andrew T., Chrostek, Matthew R., Krishna, Venkatramana D., Shiao, Maple, Toman, Nikolas G., Pearce, Clairice M., Tran, Sarah K., Sipe, Christopher J., Guo, Winston, Voth, Joseph P., Vaid, Shivanshi, Xie, Hui, Lu, Wei-Cheng, Swanson, Will, Grande, Andrew W., Schleiss, Mark R., Bierle, Craig J., Cheeran, Maxim C-J., Low, Walter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529292/
https://ncbi.nlm.nih.gov/pubmed/33002018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232858
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