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ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP

Transcription factor SNAI2 plays key roles during development and has also been known to promote metastasis by inducing invasive phenotype and tumor-initiating activity of cancer cells. However, the post-translational regulation of SNAI2 is less well studied. We performed a dual-luciferase-based, ge...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Genes Dev
المؤلفون الرئيسيون: Fan, Huijuan, Wang, Xuxiang, Li, Wenyang, Shen, Minhong, Wei, Yong, Zheng, Hanqiu, Kang, Yibin
التنسيق: Artigo
اللغة:Inglês
منشور في: Cold Spring Harbor Laboratory Press 2020
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528707/
https://ncbi.nlm.nih.gov/pubmed/32943576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.339796.120
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