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Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation

Cancer cells must adapt metabolism to thrive despite nutrient limitations in the tumor microenvironment. In this issue of Genes & Development, King and colleagues (pp. 1345–1358) report a role for transcriptional regulators of the Hippo pathway to facilitate protein scavenging and support prolif...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Sivanand, Sharanya, Vander Heiden, Matthew G.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528698/
https://ncbi.nlm.nih.gov/pubmed/33004484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343632.120
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