Predisposition of Neonatal Maternal Separation to Visceral Hypersensitivity via Downregulation of Small-Conductance Calcium-Activated Potassium Channel Subtype 2 (SK2) in Mice

BACKGROUND: Visceral hypersensitivity is a common occurrence of gastrointestinal diseases such as irritable bowel syndrome (IBS), wherein early-life stress (ELS) may have a high predisposition to the development of visceral hypersensitivity in adulthood, with the specific underlying mechanism still...

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Udgivet i:Neural Plast
Main Authors: Wu, Ke, Gao, Jing-hua, Hua, Rong, Peng, Xiao-han, Wang, Hui, Zhang, Yong-mei
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528131/
https://ncbi.nlm.nih.gov/pubmed/33029124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8876230
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