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Inducible TDG knockout models to study epigenetic regulation

Mechanistic and functional studies by gene disruption or editing approaches often suffer from confounding effects like compensatory cellular adaptations generated by clonal selection. These issues become particularly relevant when studying factors directly involved in genetic or epigenetic maintenan...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Schwarz, Simon D., Grundbacher, Eliane, Hrovat, Alexandra M., Xu, Jianming, Kuśnierczyk, Anna, Vågbø, Cathrine B., Schär, Primo, Schuermann, David
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527862/
https://ncbi.nlm.nih.gov/pubmed/33082936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.25637.2
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