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Human Cytomegalovirus Envelope Protein gpUL132 Regulates Infectious Virus Production through Formation of the Viral Assembly Compartment

The human cytomegalovirus (HCMV) UL132 open reading frame encodes a 270-amino-acid type I envelope glycoprotein, gpUL132. The deletion of UL132 (ΔUL132) from the HCMV genome results in a pronounced deficit in virus yield, with an approximately 2-log decrease in the production of infectious virus com...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Wu, Hui, Kropff, Barbara, Mach, Michael, Britt, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527726/
https://ncbi.nlm.nih.gov/pubmed/32994323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02044-20
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