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Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti-Andes orthohantavirus Neutralizing Antibodies in Patient Samples

Andes orthohantavirus (ANDV) is the etiologic agent of hantavirus cardiopulmonary syndrome (HCPS), which has a case fatality rate around 35%, with no effective treatment or vaccine available. ANDV neutralizing antibody (NAb) measurements are important for the evaluation of the immune response follow...

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Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Vial, Cecilia, Whitaker, Annalis, Wilhelm, Jan, Ovalle, Jimena, Perez, Ruth, Valdivieso, Francisca, Ferres, Marcela, Martinez-Valdebenito, Constanza, Eisenhauer, Philip, Mertz, Gregory J., Hooper, Jay W., Botten, Jason W., Vial, Pablo A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527604/
https://ncbi.nlm.nih.gov/pubmed/33042854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00444
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