Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway

BACKGROUND: Epirubicin is a first-line chemotherapeutic drug for the clinical treatment of diffuse large B cell lymphoma (DLBCL), but the overexpression of multidrug resistance (MDR) transporter proteins, especially P-glycoprotein (P-gp), renders epirubicin ineffective. Some studies reveal the poten...

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Bibliografski detalji
Izdano u:Transl Oncol
Glavni autori: Liu, Kaili, Song, Jincheng, Yan, Yue, Zou, Kun, Che, Yuxuan, Wang, Beichen, Li, Zongjuan, Yu, Wendan, Guo, Wei, Zou, Lijuan, Deng, Wuguo, Sun, Xiuhua
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press 2020
Teme:
Original article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527585/
https://ncbi.nlm.nih.gov/pubmed/33007707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100876
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