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Probing the Structure–Function relationship and amyloidogenic propensities in natural variants of apolipoprotein A-I
BACKGROUND: Apolipoprotein A-I (apoA-I) protects against atherosclerosis and participates in the removal of excess cellular cholesterol from peripheral organs. Several naturally occurring apoA-I mutations are associated with familial systemic amyloidosis, with deposition of amyloid aggregates in per...
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| Publicat a: | Biochem Biophys Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7527581/ https://ncbi.nlm.nih.gov/pubmed/33024841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100815 |
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