Longitudinal micro-computed tomography-derived biomarkers quantify non-resolving lung fibrosis in a silicosis mouse model

In spite of many compounds identified as antifibrotic in preclinical studies, pulmonary fibrosis remains a life-threatening condition for which highly effective treatment is still lacking. Towards improving the success-rate of bench-to-bedside translation, we investigated in vivo µCT-derived biomark...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dekoster, Kaat, Decaesteker, Tatjana, Berghen, Nathalie, Van den Broucke, Sofie, Jonckheere, Anne-Charlotte, Wouters, Jens, Krouglov, Anton, Lories, Rik, De Langhe, Ellen, Hoet, Peter, Verbeken, Erik, Vanoirbeek, Jeroen, Vande Velde, Greetje
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527558/
https://ncbi.nlm.nih.gov/pubmed/32999350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73056-6
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