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Calibrating the Bacterial Growth Rate Speedometer: A Re-evaluation of the Relationship Between Basal ppGpp, Growth, and RNA Synthesis in Escherichia coli

The molecule guanosine tetraphophosphate (ppGpp) is most commonly considered an alarmone produced during acute stress. However, ppGpp is also present at low concentrations during steady-state growth. Whether ppGpp controls the same cellular targets at both low and high concentrations remains an open...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Imholz, Nicole C. E., Noga, Marek J., van den Broek, Niels J. F., Bokinsky, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527470/
https://ncbi.nlm.nih.gov/pubmed/33042085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.574872
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