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High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner

There is a strong association between obesity and colorectal cancer (CRC), especially in men, whereas estrogen protects against both the metabolic syndrome and CRC. Colon is the first organ to respond to high-fat diet (HFD), and estrogen receptor beta (ERβ) can attenuate CRC development. How estroge...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Hases, L., Archer, A., Indukuri, R., Birgersson, M., Savva, C., Korach-André, M., Williams, C.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527340/
https://ncbi.nlm.nih.gov/pubmed/32999402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73166-1
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