The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis

Costunolide, a natural sesquiterpene lactone, has multiple pharmacological activities such as neuroprotection or induction of apoptosis and eryptosis. However, the effects of costunolide on pro-survival factors and enzymes in human erythrocytes, e.g. glutathione and glucose-6-phosphate dehydrogenase...

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Publicat a:Apoptosis
Autors principals: Ghashghaeinia, Mehrdad, Koralkova, Pavla, Giustarini, Daniela, Mojzikova, Renata, Fehrenbacher, Birgit, Dreischer, Peter, Schaller, Martin, Mrowietz, Ulrich, Martínez-Ruiz, Antonio, Wieder, Thomas, Divoky, Vladimir, Rossi, Ranieri, Lang, Florian, Köberle, Martin
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527323/
https://ncbi.nlm.nih.gov/pubmed/32638182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-020-01620-6
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