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Evolutionary Arms Race between Virus and Host Drives Genetic Diversity in Bat Severe Acute Respiratory Syndrome-Related Coronavirus Spike Genes

The Chinese horseshoe bat (Rhinolophus sinicus), reservoir host of severe acute respiratory syndrome coronavirus (SARS-CoV), carries many bat SARS-related CoVs (SARSr-CoVs) with high genetic diversity, particularly in the spike gene. Despite these variations, some bat SARSr-CoVs can utilize the orth...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Guo, Hua, Hu, Bing-Jie, Yang, Xing-Lou, Zeng, Lei-Ping, Li, Bei, Ouyang, Songying, Shi, Zheng-Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527062/
https://ncbi.nlm.nih.gov/pubmed/32699095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00902-20
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