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Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8

The Human T-cell leukemia virus type 1 (HTLV-1) orf I-encoded accessory protein p8 is cleaved from its precursor p12, and both proteins contribute to viral persistence. p8 induces cellular protrusions, which are thought to facilitate transfer of p8 to target cells and virus transmission. Host factor...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Donhauser, Norbert, Socher, Eileen, Millen, Sebastian, Heym, Stefanie, Sticht, Heinrich, Thoma-Kress, Andrea K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526893/
https://ncbi.nlm.nih.gov/pubmed/32997728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008879
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