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In Vitro and In Vivo Efficacies of the EGFR/MEK/ERK Signaling Inhibitors in the Treatment of Alveolar Echinococcosis

Alveolar echinococcosis (AE), caused by the larval stage of the cestode Echinococcus multilocularis, is a lethal disease in humans. Novel therapeutic options are urgently needed since the current chemotherapy displays limited efficiency in AE treatment. In this study, we assessed the in vitro and in...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cheng, Zhe, Xu, Zhijian, Tian, Huimin, Liu, Fan, Li, Xiu, Luo, Damin, Wang, Yanhai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526812/
https://ncbi.nlm.nih.gov/pubmed/32482675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-20
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