Učitavanje...
High microbiota reactivity of adult human intestinal IgA requires somatic mutations
The gut is home to the body’s largest population of plasma cells. In healthy individuals, IgA is the dominating isotype, whereas patients with inflammatory bowel disease also produce high concentrations of IgG. In the gut lumen, secretory IgA binds pathogens and toxins but also the microbiota. Howev...
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| Izdano u: | J Exp Med |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Rockefeller University Press
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526496/ https://ncbi.nlm.nih.gov/pubmed/32640466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200275 |
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