Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice

BACKGROUND: Phloretin is isolated from apple trees and could increase lipolysis in 3T3-L1 adipocytes. Previous studies have found that phloretin could prevent obesity in mice. In this study, we investigated whether phloretin ameliorates non-alcoholic fatty liver disease (NAFLD) in high-fat diet (HFD...

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Gepubliceerd in:Cell Biosci
Hoofdauteurs: Liou, Chian-Jiun, Wu, Shu-Ju, Shen, Szu-Chuan, Chen, Li-Chen, Chen, Ya-Ling, Huang, Wen-Chung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526428/
https://ncbi.nlm.nih.gov/pubmed/33014333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00477-1
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